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KMID : 0360220220630090769
Journal of the Korean Ophthalmological Society
2022 Volume.63 No. 9 p.769 ~ p.777
Short-term Outcomes and Prognostic Factor of Cataract Combined Surgery with iStent Inject versus XEN
Ma Gun-Jung

Hwang Hyung-Bin
Yim Hye-Bin
Kim Yong-Chan
Abstract
Purpose: To analyze the intraocular pressure (IOP) lowering effect, prognostic factors, and complications that occurred after iStent inject¢ç or XEN¢ç implantation in South Korea.

Methods: We retrospectively analyzed 83 eyes with glaucoma who were followed-up for more than 6 months after iStent inject¢ç or XEN¢ç implantation alone or combination with cataract surgery. The success of surgery was defined as an IOP ¡Â21 mmHg and IOP reduction ¡Ã20% from preoperative IOP.

Results: The average IOP drop rate for 6 months after surgery was 33.80% for iStent inject¢ç (group A, 24 eyes), 24.91% for XEN¢ç (group B, 15 eyes), 20.47% for combined iStent inject¢ç and cataract surgery (group A-1, 32 eyes), and 30.39% for combined XEN¢ç and cataract surgery. The cumulative success rate of 6 months after surgery was 45.5% ¡¾ 11.2% for group A, 52.8% ¡¾ 15.4% for group B, 51.9% ¡¾ 9.0% for group A-1, and 83.3% ¡¾ 10.8% for group B-1. The difference in success rates between groups A and B was not statistically significant (p = 0.574), and also between groups A-1 and B-1 (p = 0.079).

Conclusions: iStent inject¢ç and XEN¢ç both have a significant effect on lowering IOP, regardless of combining cataract surgery. XEN¢ç implantation led to a statistically significant reduction in IOP lowering medications.
KEYWORD
Glaucoma, Intraocular pressure, IStent inject, XEN gel implant
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